In the vast majority of situations, no. We developed Illumineto Spark because as sellers and marketeers ourselves, we realized there really isn't an app out there that helps sales professionals get their real work of selling done well at all. Spark can be setup and used by anyone, literally in minutes. If you are going to integrate with an external cloud storage (like Dropbox, Google Drive, etc.), then no IT won't need to be involved. Here is a great video that shows you how to connect your content sources in with Spark.
In the future, Spark will be able to tie-in to your opportunity records in Salesforce.com and other CRM systems. To do that, there will be a few minor things your IT folks will need to do.